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'Cannibalistic' Cancer Cells Gobble Up Their Own Kind

 
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Genero36



Joined: 24 Apr 2005
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PostPosted: 09/17/19 1:46 pm    ::: 'Cannibalistic' Cancer Cells Gobble Up Their Own Kind Reply Reply with quote

'Cannibalistic' Cancer Cells Gobble Up Their Own Kind in Microscopic 'Horror Films'


Quote:
New videos show human breast cancer cells in a lab dish being sucked into the belly of another cancer cell that had been treated with a chemotherapy drug. Compartments within the cannibalistic cell's structure, known as lysosomes,⁠⁠ break down the consumed cells with a fatal cocktail of digestive enzymes.

In the footage, the engulfed cells shrink down into tiny nuggets before finally disappearing.


Quote:
The researchers observed the cannibalistic behavior in cells grown in a mouse model of breast cancer, as well as human lung cancer and bone cancer cell lines grown in lab dishes.

"We found that the doxorubicin-treated cells engulfed the untreated cells, but not vice versa, nor did untreated cells engulf untreated cells," study co-author James Jackson, a professor of biochemistry and molecular biology, told Live Science in an email.

"Inhibiting this process [of cancer cell cannibalism] may provide new therapeutic opportunities," he added in a statement. For example, it's well known that breast cancer patients who have cancer cells with a normal TP53 gene suffer poor survival rates, he explained, but perhaps stopping those patients' tumor cells from eating each other might help improve their response to chemotherapy.


https://www.livescience.com/cannibalistic-cancer-cells.html



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justintyme



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PostPosted: 09/17/19 2:02 pm    ::: Reply Reply with quote

Fascinating! Thanks for sharing.



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Genero36



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PostPosted: 09/17/19 2:08 pm    ::: Reply Reply with quote

justintyme wrote:
Fascinating! Thanks for sharing.


Welcome.



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